Dimitrios Mathios, MD

Dr. Mathios is a WashU Medicine surgeon who is fellowship-trained in minimally invasive skull base surgery and neuro-oncology and cancer immunology, genetics and epigenetics. He specializes in brain tumors, ependymomas gliobastoma and other gliomas, hydrocephalus, intraventricular tumors, meningiomas, minimally invasive brain tumor surgery, orbital and periorbital tumors and transorbital skull base surgery.

He is dedicated to caring for patients with brain conditions. He utilizes advanced, high-precision microscopic and endoscopic techniques, including minimally invasive and skull base approaches, transorbital endoscopic surgery, detailed pre- and intra-operative brain mapping (including awake cognitive mapping), Gamma Knife radiosurgery and complex cranial procedures.

Dr. Mathios is committed to delivering compassionate, world-class care regionally and nationally, partnering with patients, their families and their physicians to create personalized treatment plans. His patient care philosophy is grounded in active listening, seeing each patient as a whole person — not just a condition or an image — and practicing true shared decision-making. Treatment options should be driven by the patient’s goals — not the other way around.