Adrian Shifren

Adrian Shifren, MD

Specializes In
  • Lung Health (Pulmonology)
Languages Spoken
  • English


Sees Patients For

Lung disease, rare lung disease, cystic lung disease, emphysema, COPD, pulmonary hypertension, interstitial lung disease. Dr. Shifren heads a multidisciplinary team that includes pulomonologists, rheumatologists, chest radiologists, lung pathologists and thoracic surgeons specializing in the comprehensive care of patients with these rare and complex conditions. 

Hospital Affiliations

  • Barnes-Jewish Hospital
  • Barnes-Jewish West County Hospital



Board Certifications

  • Internal Medicine
  • Pulmonary Disease
  • Critical Care Medicine

Academic Title(s)

Associate Professor, Medicine
Pulmonary and Critical Care MedicineDirector, Rare Lung Diseases ClinicDirector, Respiratory Therapy

Research Interests

The genetic determinants of emphysema. Specifically, the role of extracellular matrix molecules in predisposing to, or protecting from, emphysema. Using knockout and transgenic mouse models to investigate the mechanisms responsible for changes in emphysema susceptibility following cigarette-smoke exposure, we translate these findings to human disease by screening populations of emphysema patients for extracellular matrix molecule gene mutations that associate with clinical markers of disease.

Publications & Research

View research profile »


Fellowship (Research)

2008 Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO


2006 Pulmonary Medicine, Washington University School of Medicine, St Louis, MO

Chief Resident, Internal Medicine

2004 Washington University School of Medicine, St. Louis, MO

Medical Degree

1996 University of Witwatersrand, Johannesburg, South Africa


2001 Internal Medicine, Barnes-Jewish Hospital. St. Louis MO

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