Brenton Pennicooke, MD, MS

Brenton H. Pennicooke, MD, MS, MBA, FAANS

Spine Surgery, Neurosurgery

Top Doctors®

Specializes in

Minimally invasive spinal surgery, spinal deformity (cervical or thoracolumbar), spinal tumors/spinal oncology, artificial disc replacement, spinal stenosis, degenerative spine disease, spinal trauma

Appointments

Hospital Affiliations

  • Barnes-Jewish St. Peters Hospital

Dr. Pennicooke is a neurological spine surgeon who is fellowship-trained in complex spinal reconstruction and minimally invasive spine surgery. He specializes in artificial disc replacement, degenerative spine disease, minimally invasive spinal surgery, spinal deformity (cervical or thoracolumbar), spinal stenosis, spinal trauma, and spinal tumors/spinal oncology.

He is dedicated to delivering thoughtful, evidence-based spine care that prioritizes accurate diagnosis, individualized treatment planning, and the least invasive approach to achieve durable outcomes. He works closely with referring physicians, pain specialists, and rehabilitation teams to ensure that patients receive the right treatment at the right time, achieving optimal outcomes in a personalized way.

Dr. Pennicooke’s patient care philosophy is to provide a precise diagnosis before recommending a treatment plan. He takes the time to educate patients about their condition, discuss the full spectrum of treatment options and develop a strategy that aligns with their goals, lifestyle and long-term spinal health.

He is committed to advancing spine care through research innovation, technology development, outcomes-focused practice, and collaboration to improve how spine disease is diagnosed, treated and monitored over time.

Experience

Academic Title(s)

Assistant Professor, Neurosurgery and Orthopedic Surgery and Biomedical Engineering

Research Interests

Dr. Pennicooke is a spine fellowship-trained neurosurgeon who completed a post-residency fellowship in complex spinal reconstruction and minimally invasive spine surgery under the guidance of both neurosurgeons and orthopedic spine surgeons. His diverse training gives him a unique insight into treating a wide range of spinal diseases from significant spinal deformity/malalignment to herniated discs. Dr. Pennicooke is an expert in utilizing artificial intelligence, advanced machine learning, and causal inference to analyze patient-outcome data. His research endeavors to extensively understand the nuances of spinal disease, develop personalized patient treatment regimens and build novel clinical support tools.

Publications & Research

View research profile »

Education

Fellowship: Complex Spinal Reconstruction and Minimally Invasive Spine Surgery

2020 University of California, San Francisco, San Francisco, CA

Residency: Neurological Surgery

2019 New York-Presbyterian Hospital-Weill Cornell Medical Center and Memorial Sloan Kettering Cancer Center, New York, NY

Medical Degree

2012 Harvard Medical School, Boston, MA

Masters of Science: Molecular and Cellular

2008 The Johns Hopkins University, Baltimore, MD

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