Sid Puram, MD, PhD, FACS

Sid Puram, MD, PhD

Specializes In
  • Ear, Nose & Throat (Otolaryngology)
  • Head & Neck Surgical Oncology
Languages Spoken
  • English


Sees Patients For

Dr. Puram's clinical interests encompass head and neck cancer, HPV-related head and neck cancer, conditions of the thyroid and parathyroid glands, salivary gland tumors and disorders, and skin cancers and benign tumors of the head and neck. He is extensively trained in advanced head and neck ablative surgery, transoral robotic surgery, skull base surgery,  and microvascular reconstruction.

Hospital Affiliations

  • Barnes-Jewish Hospital
  • St. Louis Children's Hospital



Board Certifications

  • Otolaryngology

Academic Title(s)

Associate Professor, Otolaryngology-Head and Neck Surgery
Division Chief, Head and Neck Surgery

Research Interests

Dr. Puram's research focuses on understanding tumor heterogeneity in head and neck cancer, and how heterogeneity among malignant, stromal, and immune cells may contribute to prognosis, treatment response/resistance, and underlying cancer biology. He has formal training in research through a PhD in Biology and Biomedical Sciences and has advanced the field through the use of cutting edge sequencing technologies that allow tumors to be characterized at a single cell resolution.


BS, Biology and Neuroscience

2005 Massachusetts Institute of Technology (MIT), Cambridge, MA

PhD, Biology and Biomedical Science

2011 Harvard Medical School, Boston, MA

Medical Degree

2013 Harvard Medical School, Boston, MA

Post-doctoral Research Fellowship

2017 Massachusetts General / MIT Broad Institute, Boston, MA

Residency, Otolaryngology - Harvard Combined Program

2018 Massachusetts Eye and Ear Infirmary, Dana Farber Cancer Institute/Brigham and Women's Hospital, Beth-Israel Deaconess Medical Center, Boston Children's Hospital; Boston, MA

Clinical Fellowship, Head and Neck Surgical Oncology and Microvascular Free Flap Reconstruction

2019 James Cancer Center / Ohio State University, Columbus, OH